Second "Booster" dose and reopening of the vaccination centre in Esch-Belval

New recommendations for a second booster dose (or 4th dose)

Following the recommendations of the High Council for Infectious Diseases (CSMI), a second booster dose (or 4th dose) of a bivalent mRNA vaccine (Comirnaty Wuhan/B.A.1 or Spikevax Wuhan/B.A.1 or Comirnaty Wuhan/B.A. ​ 4-5 depending on availability) is recommended for the following individuals:

  • people over 60 years of age
  • people aged 12-59 with co-morbidities that put them at risk of severe forms of COVID-19,
  • immunocompromised persons,
  • pregnant women,
  • and health professionals.

The 2nd booster dose can also be offered to all other persons aged 12-59 years without risk factors and without recent infection, upon request. However, this 4th dose is not recommended for healthy people who have had an SARS-CoV-2 infection (confirmed by PCR or antigen test) after the first booster dose.

The 2nd booster dose is given at an interval of at least 4 months after the 3rd vaccination dose (or 1st booster dose), respectively after an infection. This booster dose is intended to maintain a high level of vaccine protection for the individuals concerned to prevent infection, severe forms of the disease and death.

Temporary reopening of the vaccination centre in Esch-Belval

In order to prepare the population as well as possible for possible waves of infection during the coming autumn and winter, the Luxembourg government is reopening the vaccination centre Esch-Belval as of Thursday 13 October. Opening hours are Tuesday to Friday from 7am to 7pm and Saturday from 7am to 1pm.

Booking an appointment

No further invitations will be sent by post to the persons concerned. Appointments at the vaccination centres can now be made directly at by simply entering your social security card number (matricule). Appointments can be made from 11 October onwards.

People aged 60 and over who have received an invitation from the Luxembourg government by post in the past can either make an appointment using their social security card number (matricule) as described above (from 11 October), or use the code that was sent to them and which remains valid.

As vaccination centres are temporary facilities dedicated to the vaccination against COVID-19, it is still recommended to go to a doctor or a pharmacy to get vaccinated. The list of physicians and pharmacies participating in the vaccination campaign is available at

Personalised assistance is also offered through the Helpline Santé specifically set up for this purpose under the number (+352) 247-65533.

Press release by the Ministry of Health / Ministry of State

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